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Amorsa therapeutics turku

amorsa therapeutics turku

Jeff attained his law degree from. "I am excited to join Amorsa's Board of Directors said Jeff Wiesen. Jeff served as President and Chief Executive Officer of the firm from 1994 to 1996. Our platform produces products to treat patients suffering from a range of serious diseases. SEA-bcma is a novel humanized antibody that targets the antigen bcma, developed by Seattle Genetics using their sugar-engineered antibody (SEA) technology. Every day, we push the boundaries of technology to transform medicine. We are leveraging the investment we have already made to clinically validate and de-risk actr by rapidly expanding our pipeline of actr-based therapies using commercially available and development-stage antibodies. Pear discovers, develops, and delivers clinically validated software to provide better outcomes for patients, smarter engagement and tracking tools for clinicians, and cost-effective solutions for payers. His expertise will be a tremendous asset to Amorsa as we advance our therapeutic programs.". Our product candidate actr707 is a modified actr construct that has been designed to allow the actr T cells to behave more favorably in immunosuppressive tumor microenvironments commonly found in solid tumor cancers. We are currently evaluating the safety, tolerability, and anti-lymphoma activity of actr087 used in combination with rituximab in adult patients with CD20 B cell relapsed or refractory NHL in an ongoing Phase I, multi-center, open-label clinical trial called attck-20-2.

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Anti-tumor activity has been observed in the early stages of this trial. This is the first clinical product candidate arising from our strategic collaboration with Seattle Genetics, as well as our first clinical product candidate incorporating a novel antibody. Additional Product Candidates, we are exploring the potential of our universal actr platform in combination with a wide range of tumor-targeting antibodies to pursue hematologic and solid tumor cancers with significant unmet medical needs. PDTs are designed to directly treat disease, tested for safety and efficacy in randomized clinical trials, evaluated by the FDA, and prescribed by healthcare providers. Learn more at clinicaltrials. The leader in Prescription Digital Therapeutics. At Massachusetts Institute of Technology. Skip to content, redefining Medicine, prescription Digital Therapeutics for the treatment of serious disease, watch the Video. About Amorsa Therapeutics, amorsa is a neuropharmaceutical company pioneering the development and commercialization of breakthrough treatments for nervous system disorders including treatment-resistant depression and moderate-to-severe pain. Amorsa Therapeutics, inc., a neuropharmaceutical company pioneering the development of breakthrough treatments for nervous system disorders, is pleased to announce the appointment of Jeffrey Wiesen to its Board of Directors.

amorsa therapeutics turku

earned his.S. While HER2 is overexpressed in a subset of breast and gastric cancers, it is found at low levels on certain essential tissues within the body. "We are thrilled to welcome Jeff to our Board said Joe Blanchard, President and Chief Executive Officer of Amorsa. Trastuzumab is a humanized monoclonal antibody that targets the HER2 cell surface receptor, and is currently approved to treat HER2 breast cancers and HER2 gastric cancers alone and in combination with chemotherapy. Unum Therapeutics' Expanded Access Policy. Gov, multiple Myeloma, aCTR087 SEA-bcma, our third clinical product candidate is actr087 used in combination with SEA-bcma, which we plan to test in adult patients with relapsed or refractory multiple myeloma. We are currently testing the safety, tolerability, and anti-myeloma activity of actr087 used in combination with SEA-bcma in adult patients with r/r multiple myeloma in a Phase I, multi-center, open-label clinical trial called attck-17-01. Actr087 is an actr construct that uses a 4-1BB co-stimulatory domain. As the former Chair of Mintz Levin's Life Sciences Practice, Jeff has been a leader in the biotechnology industry since its inception and has actively assisted numerous companies ranging from newly formed start-up ventures to public pharmaceutical companies. Our Pipeline, multiple products, therapeutic areas, and development stages. ...

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Pears second product candidate, reSET-O for the treatment of Opioid Use Disorder, is currently under review by the FDA with Breakthrough Designation. Rituximab is a CD20 targeting chimeric monoclonal antibody that is FDA-approved to treat non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia, both malignancies that affect the B cells. . These data will also inform a multi-center Phase II clinical paksu pillu omat kuvat alastonkuvia trial exploring actr087 used in combination with rituximab in adult patients following treatment with a CD19 CAR therapy who have progressive disease. Our pipeline is focused on product candidates across development stages that demonstrate large, clinically-relevant treatment effects. Prescription Digital Therapeutics, software to treat human disease, prescription Digital Therapeutics, or PDTs, are software-based disease treatments. Pears lead product, reSET, works with face-to-face therapy to treat Substance Use Disorder, and was the first PDT to receive market authorization from the FDA to improve disease outcomes. SEA-bcma is engineered to enhance its binding to actr087, providing additional rationale for this novel-novel combination. Actr707 was identified through a comprehensive high-throughput screening effort aimed at identifying constructs with properties that may function particularly well in a solid tumor setting (including increased proliferation, cytokine secretion, and persistence). As a first-step, we are currently testing actr707 as a proof of concept in a Phase I multi-center open label clinical trial, attck-20-03, in combination with rituximab, to enable rapid assessment of this alternative construct. Our cross-functional team operates at the intersection of biology and software technology. "Jeff is an industry veteran and has successfully led the structuring and negotiation of some of the biotech industry's most successful strategic alliances, venture financings, M A transactions and public offerings. In preclinical studies, we have shown antigen-specific killing of HER2-overexpressing cell lines with actr707 used in combination with trastuzumab, without observing cytotoxic effects in normal cells expressing low amounts of HER2. To learn more about Unum Therapeutics' Expanded Access policy, please view our guidelines. These data have informed ongoing development, most immediately in defining the preliminary recommended phase 2 dose (RP2D) for the expansion cohort in this clinical trial. In addition, Amorsa has attracted leading neuroscience and pain management experts to join its Scientific and Clinical Advisory Board. Non-Hodgkin Lymphoma (NHL aCTR087 rituximab, our most advanced product candidate is actr087 used in combination with rituximab. Contact: Joseph Blanchard, View original content with multimedia: ml, source Amorsa Therapeutics. He has been a frequent lecturer for the Biotechnology Industry Organization, the American Law Institute, and the Massachusetts Continuing Legal Education Foundation, as well as numerous symposia on biotechnology strategic alliances. At Pear, our mission is clear: we are pioneers in PDTs. We expect to leverage data from this Phase I clinical trial to inform future studies combining actr707 with a variety of antibodies targeting different cancers, including one combination, actr707 used in combination with trastuzumab, that we plan to evaluate for treatment of HER2 cancers. Actr707 Trastuzumab for HER2 Cancers, we are currently in late-stage preclinical development of actr707 used in combination with trastuzumab for the treatment of patients with cancers that overexpress HER2. Amorsa is dedicated to improving the health and well-being of patients affected by nervous system disorders. Amorsa s Technology Building on ketamines proven success as a rapid-acting antidepressant and potent analgesic, Amorsa is developing novel non-invasive therapeutic agents based on proprietary analogs of ketamine. Is actively using 16 technologies for its website. These include Viewport Meta, IPhone / Mobile Compatible, and Google Font API.

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